![]() ![]() MethodsĮxpired gases of seven lung-lavaged pigs were analyzed at different lung conditions using main-stream VC and multiple inert gas elimination technique (MIGET). The aim of this work was to validate VD Bohr using PACO 2 derived from volumetric capnography (VC) against VD Bohr with PACO 2 values obtained from the standard alveolar air formula. Increased physiological dead space and air volume indicate abnormalities of the alveoli.Bohr’s dead space (VD Bohr) is commonly calculated using end-tidal CO 2 instead of the true alveolar partial pressure of CO 2 ( PACO 2).In addition, particles larger than 2.0 μm in the inhaled air are trapped in this area before entering the alveoli.The respiratory air is saturated by water vapor in the anatomical dead space and enters the alveoli.Figure: Bohr’s Equation Significance of the Dead Space The physiologically dead space can be determined by Bohr’s equation. Normal Value: In the case of a normal person, the volume of air in the anatomical dead space is almost equal to the volume of air in the physiological dead space.( Unused ventilated air = Unused air in the air sacs of the lungs + Excess received air ) Physiological dead space = Anatomical dead space + Unused ventilated air Figure: Physiological and anatomical dead space The air that is trapped at any point in the respiratory tract that does not participate in the gaseous exchange is called physiological dead space. Normal Value: The volume of anatomical dead space air is usually 150 ml and it is 20-30% of tidal volume (TV). ![]() The volume of air that is confined to the transport area of the respiratory tract and does not participate in the exchange of gas is called anatomical dead space. Respiratory dead space is generally two types – Anatomical dead space and Physiological dead space. The part of the respiratory tract where the trapped air does not participate in gaseous exchange is called respiratory dead space. ![]()
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